EDEM1

ER degradation-enhancing alpha-mannosidase-like 1 (EDEM1) is a gene that was identified by multiple users in many docs spread across several different missions. One of EDEM1's functions is to route misfolded glycoproteins for degradation--that is, this protein serves an important role in protein homeostasis. Interestingly enough, the EDEM1 protein itself is an N-glycosylated protein and is a target of N-glycanase. Hence N-glycanase controls the degradation of this protein which affects the degradation of other proteins. Help us explore the literature around an interesting clue that YOU found.

This doc set needs your help. Please sign in here.

Community progress on this set:

80.67%
Top doc set contributors:
  • ScreenerDB

  • Judy_E

  • ckrypton

  • AJ_Eckhart

  • skye

Group Statistics
  1. Total number of contributors: 26

  2. Total documents: 50

  3. Current average f-score: 0.619

  4. Start date:

  5. End date: in progress

Top contributor word cloud: