Composed of ~483 abstracts, the CDG doc set was one of the largest sets in Mark2Cure’s Campaign for NGLY1. This set was completed sometime on Tuesday night (07/28) and is the second doc set to be completed by the Mark2Cure community (the first one being the Alacrima set).
While we work on preparing the next doc set for release, there are still two doc sets available right now to the Mark2Cure community, both of which are over 60% complete.
The FBX/Engase Set
F-box protein 2 (FBX2) and endo-beta-N-acetylglucosaminidase (ENGASE) are two genes which were identified to be potentially relevant to NGLY1 deficiency. There are very few papers linked to these two genes; but they may hold valuable clues regarding other relevant topics to search. Help finish this set.
The O-linked glycosylation disorders set
Can researchers gain insight on the genes involved in N-linked glycosylated protein degradation and compensatory mechanisms by studying O-linked glycosylation disorders? Are there treatment strategies for O-linked glycosylation disorders that might apply to NGLY1 deficiency? Help finish this set.
We’ll have a big news update for the community next week! Until then, here’s a round of applause for your incredible accomplishment: